About me

I received my Ph.D. from the Department of Nanophysics at the University of Toulouse, France, in 2009, and have been an associate professor of that department since 2011. Meanwhile, I was a postdoctoral researcher with Prof. Michael Levitt at Stanford University. During this period, I adapted my Ph.D. work, which aimed to develop computational programs for induced fit accommodation of biomolecules, to the prediction of large-scale motions in motor proteins. 

My research is now focused on the development of new methodologies dedicated to the screening of mutations in oncoproteins. I notably work on Ras oncoproteins in collaboration with the Cancer Research center of Toulouse to propose new therapeutic strategies. More generally, I also use mutations to understand protein (mal)function associated to disease and to investigate the mechanisms of drug action and resistance.

 

Vitae

Professional situation

2011               Associate Professor in Physics, University of Toulouse.

2009-2011     Post-doctoral fellow, Pr. Michael Levitt's group, Stanford University, USA.
                      "New methodology to explore largefunctional motions in torsional space and application to ATP
                      molecular motors"
 
2006-2009     Ph.D. Thesis in Nanophysics, Physical-Biology Interface, University of Toulouse.
                     "New methodological approach tor the treatment of conformational flexibility in biomolecular
                      interactions: the Static Modes"

 

Education

2009             Ph.D. Thesis in Nanophysics, Physical-Biology Interface, University of Toulouse.
                       Defended at LAAS-CNRS, Toulouse. Directors: Pr M. Djafari Rouhani, Dr A. Estève.
 
2005               MS in Nanophysics, Nanocomponents, Nanomeasures, INSA & University of Toulouse.
                     
2003               BS in Fundamental Physics, University of Toulouse