Etienne Dague, PhD-HDR, PharmD LAAS-CNRS         Publications list

CNRS Research Fellow 7 avenue du Colonel Roche

ORCID ID: 0000-0003-3290-9166 31400 Toulouse, France

Born on 08/10/1978 +33 5 61 33 78 41 

Married, 2 childs, edague@laas.fr


CURRENT POSITION

-        CNRS Researcher: Systems Analysis and Architecture Laboratory, Engineering for Life Sciences team (ELIA), Toulouse, France

-        Adjunct Professor: University of Regina, Canada. Faculty of Graduate Studies and Research

 

ACADEMIC BACKGROUND

2011:          Habilitation to Lead Research, University of Toulouse, France

2006:          Doctorate in Sciences, University of Lorraine, France

2003:          State Diploma of Doctorate in Pharmacy, University of Lorraine, France

2003:          MSc: Water Chemistry and Microbiology, University of Lorraine-University of Poitiers, France

2001:          Master's degree in Biological and Medical Sciences, University of Lorraine, France

 

PREVIOUS POSITIONS

2011-2016: Head of the team " Nanocardiology and Biophysics of Cancer Cells (NBC) " at ITAV-CNRS (Institut des Technologies Avancées en Sciences du Vivant), Toulouse, France

2002-2007: Army pharmacist-chemist under commitment to serve in the operational reserve, 1st medical regiment of Metz, France

2006-2007: Post-doctoral researcher, Catholic University of Louvain, Louvain-la-Neuve, Belgium

2003-2006: PhD student on the subject "Physico-chemistry of bacterial-aqueous solution interfaces", thesis under the supervision of Dr. Gaboriaud, Prof. Jorand and Prof. Block, University of Lorraine, France

2001-2002: External in pharmacy, Neufchâteau regional hospital, France

 

BIBLIOMETRY

I am the author of 66 articles, 11 journals or book chapters published in international peer-reviewed scientific journals, and 3 patents. I have an H-index of 32, my work has been cited more than 2750 times. I have been invited to 18 international conferences, presented 42 oral communications and 46 posters in 66 international scientific conferences. I have edited more than 110 papers for PlosOne as an academic editor.

 

RESEARCH FUNDING

2019-2020: MITACS global link, an exchange program between France and Canada, obtaining a scholarship for a year's thesis in France of Easter Ndlovu

2018-2021: ANR PRC GRAPHICS, 350 k€. Project entitled " Characterization of the architecture of GPCRs on the surface of living cells by Atomic Force Microscopy in single molecule force spectroscopy mode ", selected by Evaluation Committee 11 (Biochemistry, Biophysics, Molecular and Structural Biology)

2017:          AURORA exchange program between France and Norway, funded by Campus France, on the project entitled "Elucidating interaction capacities of micoorganisms using sensitive force probes".

2016-2022: Industrial contract with the company Lallemand, 201 k€. Project entitled "LallWall, Understanding the architecture of industrial yeasts by integrating biochemical, molecular and biophysical approaches".

2016 :          Åsgard exchange program between France and Norway, financed by the French Embassy in Norway.

2015-2019: ECOS-North France-Mexico cooperation program, financing of 8 missions, on the project entitled "NanoPalpation for medical diagnosis".

2015-2017: Initiatives of Excellencies IDEX Toulouse Transversality, 50 k€. Project entitled "SMiRCH: Force spectroscopy for Single Molecule ResearCH at the surface of living cells".

2014-2016: Funding of the FRM (Foundation for Medical Research), 90 k€. Project entitled "Atomic Force Microscopy on living cardiomyocytes".

2013-2016: Cofinancing of a thesis by the PRES of Toulouse and the Midi-Pyrénnées Region, 130 k€. Project entitled "MIFACARD: Atomic Force Microscopy for CARDiology".

2013-2015: Laboratory-company research operation, funded by the Midi-Pyrénnées Region, 28 k€. Project entitled "BACT'EAU: transfer mechanisms of deformable bacteria in membrane filtration processes used in water production". Project carried out in collaboration with the company Polymem.

2012-2015: ANR JCJC AFMYST, 182 k€. Project entitled "Biophysical, biochemical and biomolecular study of the yeast wall", selected by the Evaluation Committee SVSE5 (Physique-Chimie du Vivant et Innovation Biotechnologique).

2010-2013: CNRS interdisciplinary program CNRS physics-chemistry-biology interface, support for risk taking, 50 k€. Project entitled "THERMOBIOAFM: protein unfolding at controlled temperature by AFM force spectroscopy".

2010-2012: Inter-regional scientific project funded by ANR NanoInnov C'Nano Grand Sud Ouest, 20 k€. Project entitled "APTATIPS: antibody-aptamers comparison for single molecule force spectroscopy experiments".

 

AWARDS AND GRANTS

2014:          ICNano Mexico travel grant to give a plenary lecture at ICNano 2014 (International Congress on Application of Nanotechnology), Mexico City, Mexico.

2013:          George McCracken Infectious Disease Travel Fellowship from the American Society of Microbiology (ASM) to present my work at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

2011:          Travel grant from JPK Instruments, obtained to give a lecture at the NanoBioView congress: Scanning probe microscopy and optical tweezers in life sciences, Berlin, Germany

2010:          Travel grant from the Centre Franco-Indien de la Promotion de la Recherche Avancée to give a lecture at the Hope in Red (Host pathogen interaction in respiratory infectious diseases) conference, Bengalore, India.

2008:          Thesis Prize of the National Academy of Pharmacy, obtained for presenting the best thesis in Pharmaceutical Sciences, Paris, France

2007:          Thesis Prize of the Academy of Sciences of Lorraine, Nancy, France

2007:          Dissertation prize from the University of Lorraine, Nancy, France

2004:          IHP (Improving the Human Potential) travel grant to attend the BIO- IMED II (Biofilms in industry, medicine and environmental biotechnology) congress, Galway, Ireland.

 

 

SCIENTIFIC EXPERTISE ACTIVITIES

2019:          Member of the editorial board of the scientific journal “The cell surface” (Elsevier)

2018:          Project evaluator for Flanders Fundation Research, Belgium

2014-2016: Evaluator of 3 projects for the Scientific Council of the Ile-de-France region, and one project for the Scientific Council of the Franche-Comté region

2012 :          PlosOne Academic Editor, edition of 110 articles

2010- :         Reviewing articles (˃100) for the following journals: Physical chemistry chemical physics, Journal of Molecular Recognition, Journal of Structural Biology, Biophysical Journal, Biomacromolecules, Biofouling, Biomaterials, JACS, Future medicine: nanomedicine, Micron, BBA biomembrane, BBA GS, PlosOne, Nanoscale, Trends in Microbiology, Soft Matter, M Sphere, Micromachines, etc...

2010-2019: Evaluator of more than 20 projects for the FNRS (National Fund for Scientific Research), Belgium

2010 :          Evaluator of a project at ANR at Evaluation Committee 10 (Nanosciences)

2009:          Evaluator of 3 projects at the ANR in the P3N program (Nanosciences, Nanotechnologies, Nanosystems Program)

 

ORGANIZATION OF SCIENTIFIC CONFERENCES

2020:          Organizer of a Symposium (Fabrication and applications of BioMEMS-NEMS, Labs-on-a-chip and Organs-on-a-chip), held during the 29th IMRC (International Material Research Conference), Cancun, Mexico CANCELLED

2020:          Member of the scientific committee of the 3rd NanoInBio (Advances for life and material sciences) congress, organized in Gosier, Guadeloupe, France; Postponed October 2020

2020:          Organizer of the plenary days of the GDR B2I (Bio Engineering of Interfaces), Toulouse, France; CANCELLED, Postpone in 2021

2019:          Organizer of the C2 Symposium (Fabrication and applications of BioMEMS-NEMS, Labs-on-a-chip and Organs-on-a-chip), held during the 28th IMRC (International Material Research Conference), Cancun, Mexico

2018:          Member of the organizing committee and the scientific committee of the 2nd NanoInBio (Advances for life and material sciences) congress, organized in Gosier, Guadeloupe, France.

2018:          Organizer and member of the scientific committee of the BioPhysAdh congress (International conference on the Biophysics of the microbial adhesion), Toulouse, France

2018:          Organizer of a dedicated session (Dimensional metrology of nanoparticles) that took place during the Nanotech France 2018 congress, Paris, France

2016-2019: Member of the scientific committee of the annual ICONAN (International Conference on Nanomedicine and Nanobiotechnology) congress

2016:          Member of the organizing committee and the scientific committee of the 1st NanoInBio (Advances for life and material sciences) congress, organized in Gosier, Guadeloupe, France.

2014:          Member of the organizing committee of the forum of Local Probe Microscopy, Montauban, France

2013:          Organizer of an INSERM workshop entitled "Cellular and molecular Nanomechanics as probed by Atomic Force Microscopy", Paris, France

2013:          Organization of a thematic day entitled "Atomic Force Microscopy: Themes and Variations", within the FERMAT Research Federation, Toulouse, France

 

MENTORING ACTIVITIES: PhD supervision

2019-2022: Co-supervision of a thesis funded by ANR, carried out by Irem Demir, on the subject: Nano-investigation of bubble-microorganisms interactions.

2019-2022: Co-supervision of a thesis in international cooperation with Canada, Univeristy of Regina, carried out by Easter Ndvolu on the topic “C. albicans interactions with cnacerous cells”.

2017-2020: Co-direction of a ministerial thesis (MEGEP doctoral school), directed by Ibrahima Dramé, on the subject "Role of pills in the adhesion of Lacotococcus lactis".

2017-2020: Supervision of a 6-month stay of a thesis student in Portugal, Mafalda Cavalheiro, on the topic "From nanoscale to genome-wide uncovering of the master regulators of C. glabrata surface adhesion and biofilm formation".

2016-2020: Co-direction of a thesis in international co-supervision with Mexico, financed by CONACYT Mexico, carried out by Sergio Proa, on the subject "Automation of measurements by Atomic Force Microscopy".

2013-2016: Direction of a PRES Toulouse - Région Midi-Pyrénnées thesis, carried out by Véronique Lachaize, on the subject "Nanotechnologies for the study of nanomechanical properties and the micro-organisation of interfaces of living cardiomyocytes".

2012-2015: Supervision of a thesis student on the BACT'EAU project, Arthur Gaveau, on the subject "Study of the transfer mechanisms of deformable bacteria in frontal microfiltration".

2012-2014: Direction of a thesis co-funded by ANR and the French Defence Procurement Agency (DGA), carried out by Cécile Formosa, on the subject "Understanding the action targets of new antibacterial molecules using bionanotechnologies".

2011-2014: Co-direction of a CIFRE thesis with the Lallemand company, carried out by Marion Schiavone on the subject "Characterization of the molecular architecture and biophysical properties of yeast walls".

2010-2013: Co-director of a DGA thesis, directed by Louise Chopinet, on the subject "Study of the mechanism of electrotransfer of molecules in cells and tissues by advanced microscopy techniques".

2009-2012: Co-director of a PRES thesis in Toulouse, directed by Eric Jauvert, on the subject "Nanotechnologies for biology, application to bacterial-bacteriophage interactions".

2008-2011: Co-direction of an INRA thesis, directed by Doan Thanh Lam Le, on the subject "Identification of the physico-chemical and biological determinants involved in the adhesion of Lactococcus lactis to the intestinal mucosa".

 

MENTORING ACTIVITIES: Post-doctoral researchers

2017-2018: Postdoc ANR GRAPHICS, Rosie Dawaliby, on the subject "Characterization of GPCR architecture on the surface of living cells by Atomic Force Microscopy".

2015-201 :   Postdoc financed by the Lallemand company, directed by Marion Schiavone, on the subject "LallWall, Understanding the architecture of industrial yeasts by integrating biochemical, molecular and biophysical approaches".

2014-2016: Postdoc Fondation Recherche Médicale, by Georges Smolyakov, on the subject "Multiparametric AFM of living cardiomyocytes".

2014-2018: Multi-support post-doc, by Flavien Pillet, on the subject of "Eradication of bacteria by electroporation".

2013:          ANR AFMYST post-doc, by Flavien Pillet, on the subject "Biophysical, biochemical and biomolecular study of the yeast wall".

2012:          Post-doc ANR AFMYST, by Sébastien Gauthier, on the subject "Biophysical, biochemical and biomolecular study of the yeast wall".

 

SCIENTIFIC COLLABORATIONS

International collaborations

-    Dr. Adrian Martinez-Rivas, Instituto Polytechnico Nacional, Mexico (2015-pending) / 1 patent, 2 publications, 1 PhD thesis cosupervised and defended (february 2020)

-    Prof. Marit Sletmoen, Norwegian University of Sciences and Technology (NTNU), Norway (2015-ongoing) / 1 publication, exchange of masters and doctoral students

-    Dr. Martina Baum, Univeristy of Kiel, Germany (2018-ongoing) / 1 publication submitted, exchange of a master student

-    Prof. Tanya Dahms, University of Regina, Canada (2018-in-progress) / 1 book chapter, 1 publication submitted, thesis exchange student, Sabbatical hosting.

-    Prof. Miguel Texeira, University of Lisboa, Portugal (2018-ongoing) / 1 publication submitted, exchange of a thesis student

-    Prof. Alistair Brown and Prof. Carol Munro, University of Aberdeen, UK (2014-2018) / 3 publications

-    Prof. Nadica Ivosevic DeNardis, Ruder Boskovic Institute, Zagreb, Croatia (2018-ongoing) / 1 publication

-    Prof. Marcos De Morais Jr, Universidad Federal de Pernambuco, Brazil (2016-ongoing) / 1 publication

 

 

National collaborations

-    Prof. Juan Pelta and Prof. Sid Labdi, LAMBE, University of Evry, France (2014-2016) / 1 publication

-    Prof. Jean-Paul Latgé, Institut Pasteur, Paris (2006-2013) / 4 publications

-    Dr. M. Lavie-Richard, Institut Micalis, INRA Jouy-en-Josas (2012-2015) / 1 publication

-    Prof. Raphaël Duval, SRSMC, University of Lorraine, France (2011-2015) / 11 publications

-    Prof. Christophe D'Enfert, Pasteur Institute, Paris (2014-2018) / 3 publications

-    Dr. Mickaël Desvaux, University of Clermont-Auvergne (2018-2019) / 1 publication

 

Local collaborations (outside the laboratory)

-    Pr. Clémence Coetsier, LGC, University of Toulouse (2019-ongoing)

-    Dr. Emmanuel Flahaut, CIRIMAT, University of Toulouse (2019-ongoing)

-    Prof. Eric Oswald, CHU of Toulouse (2017-in progress)

-    Prof. Marie-Pierre Rols, IPBS, University of Toulouse (2011-ongoing) / 8 publications

-    Prof. Laurence Ressier, LPCNO, INSA of Toulouse, France (2009-2012) / 5 publications

-    Prof. Jean-Marie François and Dr. Hélène Martin-Yken, TBI, INSA de Toulouse, France (2008-ongoing) / 10 publications

-    Prof. Christel Causserand, LGC, University of Toulouse (2012-2015) / 1 publication

-    Dr. Muriel Mercier-Bonin, Toxalim, University of Toulouse (2008-2011) / 4 publications

-    Dr. Céline Galès and Dr. Constandina Arvanitis, I2MC, University of Toulouse (2011-ongoing) / 5 publications

-    Dr. Mickaël Castelain, TBI, INSA of Toulouse, France (2015-ongoing) / 2 publications

-    Dr. Mathieu Castex, Société Lallemand, Toulouse (2011-ongoing) / 3 publications